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PDB: 1 results

2HHH
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BU of 2hhh by Molmil
Crystal structure of kasugamycin bound to the 30S ribosomal subunit
Descriptor: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Schluenzen, F.
Deposit date:2006-06-28
Release date:2006-09-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006

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