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PDB: 2 results

9C8T
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BU of 9c8t by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with AMPPNP and compound 2
Descriptor: 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, Cyclic GMP-AMP synthase, GLYCEROL, ...
Authors:Wang, L, Sietsema, D.
Deposit date:2024-06-12
Release date:2025-04-02
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural insight into the cGAS active site explains differences between therapeutically relevant species.
Commun Chem, 8, 2025
9C8N
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BU of 9c8n by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with AMPPNP and compound 1
Descriptor: 1-[(1S)-6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-methoxyethan-1-one, Cyclic GMP-AMP synthase, GLYCEROL, ...
Authors:Wang, L, Sietsema, D.
Deposit date:2024-06-12
Release date:2025-04-02
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insight into the cGAS active site explains differences between therapeutically relevant species.
Commun Chem, 8, 2025

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PDB entries from 2025-07-09

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