9C8T
 
 | Crystal Structure of human cyclic GMP-AMP synthase in complex with AMPPNP and compound 2 | Descriptor: | 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, Cyclic GMP-AMP synthase, GLYCEROL, ... | Authors: | Wang, L, Sietsema, D. | Deposit date: | 2024-06-12 | Release date: | 2025-04-02 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural insight into the cGAS active site explains differences between therapeutically relevant species. Commun Chem, 8, 2025
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9C8N
 
 | Crystal Structure of human cyclic GMP-AMP synthase in complex with AMPPNP and compound 1 | Descriptor: | 1-[(1S)-6,7-dichloro-1-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-methoxyethan-1-one, Cyclic GMP-AMP synthase, GLYCEROL, ... | Authors: | Wang, L, Sietsema, D. | Deposit date: | 2024-06-12 | Release date: | 2025-04-02 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insight into the cGAS active site explains differences between therapeutically relevant species. Commun Chem, 8, 2025
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