9BTN
 
 | |
9BTM
 | | NRas 1-169 Q61R in Complex with Shoc2 80-582 | | Descriptor: | GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, Leucine-rich repeat protein SHOC-2, ... | | Authors: | Hauseman, Z.J, King, D, Viscomi, J, Fodor, M. | | Deposit date: | 2024-05-15 | | Release date: | 2025-04-02 | | Last modified: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
Nature, 642, 2025
|
|
9BTP
 | | Structure of human SHOC2 in complex with a small molecule inhibitor (S)-5 | | Descriptor: | (2S)-{2-[(4-chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl}[(2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)amino]acetic acid, Leucine-rich repeat protein SHOC-2, POTASSIUM ION | | Authors: | Dhembi, A, Hauseman, Z.J, King, D. | | Deposit date: | 2024-05-15 | | Release date: | 2025-04-02 | | Last modified: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
Nature, 642, 2025
|
|
9OVJ
 | | Structure of human SHOC2 in complex with a small molecule inhibitor (R)-5 | | Descriptor: | (2R)-{2-[(4-chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl}[(2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)amino]acetic acid, Leucine-rich repeat protein SHOC-2, POTASSIUM ION | | Authors: | Dhembi, A, Hauseman, Z.J, King, D. | | Deposit date: | 2025-05-30 | | Release date: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
Nature, 642, 2025
|
|
