9EK0
 
 | | Human M5 muscarinic acetylcholine receptor complex with mini-Gq and iperoxo | | Descriptor: | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Burger, W.A.C, Mobbs, J.I, Thal, D.M. | | Deposit date: | 2024-11-30 | | Release date: | 2025-10-08 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Cryo-EM reveals an extrahelical allosteric binding site at the M 5 mAChR.
Nat Commun, 16, 2025
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9EJZ
 | | Human M5 muscarinic acetylcholine receptor complex with mini-Gq, agonist acetylcholine and positive allosteric modulator VU6007678 | | Descriptor: | ACETYLCHOLINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Burger, W.A.C, Mobbs, J.I, Thal, D.M. | | Deposit date: | 2024-11-30 | | Release date: | 2025-08-13 | | Last modified: | 2025-10-08 | | Method: | ELECTRON MICROSCOPY (2.06 Å) | | Cite: | Cryo-EM reveals an extrahelical allosteric binding site at the M 5 mAChR.
Nat Commun, 16, 2025
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