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PDB: 5 results
9ED9
SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State III - checkpoint)
Descriptor:
CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, PAM-distal Target Strand, ...
Authors:
Kiernan, K.A
,
Taylor, D.W.
Deposit date:
2024-11-16
Release date:
2025-06-18
Last modified:
2025-07-09
Method:
ELECTRON MICROSCOPY (2.95 Å)
Cite:
Visualization of a multi-turnover Cas9 after product release.
Nat Commun, 16, 2025
9EDA
SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State IV - product)
Descriptor:
CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, PAM-distal Target Strand, ...
Authors:
Kiernan, K.A
,
Taylor, D.W.
Deposit date:
2024-11-16
Release date:
2025-06-18
Last modified:
2025-07-09
Method:
ELECTRON MICROSCOPY (2.88 Å)
Cite:
Visualization of a multi-turnover Cas9 after product release.
Nat Commun, 16, 2025
9EDB
SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State V - dissociated)
Descriptor:
CRISPR-associated endonuclease Cas9/Csn1, Non-target Strand, Target Strand, ...
Authors:
Kiernan, K.A
,
Taylor, D.W.
Deposit date:
2024-11-16
Release date:
2025-06-18
Last modified:
2025-07-09
Method:
ELECTRON MICROSCOPY (3.1 Å)
Cite:
Visualization of a multi-turnover Cas9 after product release.
Nat Commun, 16, 2025
9EAK
SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State I - pre-activation)
Descriptor:
CRISPR-associated endonuclease Cas9/Csn1, DNA (Non-target strand), DNA (Target Strand), ...
Authors:
Kiernan, K.A
,
Taylor, D.W.
Deposit date:
2024-11-11
Release date:
2025-06-18
Last modified:
2025-07-09
Method:
ELECTRON MICROSCOPY (2.76 Å)
Cite:
Visualization of a multi-turnover Cas9 after product release.
Nat Commun, 16, 2025
9EAL
SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State II - precleavage)
Descriptor:
CRISPR-associated endonuclease Cas9/Csn1, DNA (Non-target strand), DNA (Target Strand), ...
Authors:
Kiernan, K.A
,
Taylor, D.W.
Deposit date:
2024-11-11
Release date:
2025-07-09
Method:
ELECTRON MICROSCOPY (2.83 Å)
Cite:
Visualization of a multi-turnover Cas9 after product release.
Nat Commun, 16, 2025
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PDB entries from 2025-08-20