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PDB: 7 results
8XGJ
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BU of 8xgj by Molmil
Human Cx36/GJD2 gap junction channel in complex with mefloquine.
Descriptor: (11R,12S)- Mefloquine, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-15
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024
8XH9
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BU of 8xh9 by Molmil
Human Cx36/GJD2 (Ala14 deletion mutant) gap junction channel prepared with mefloquine, showing no bound mefloquine
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-17
Release date:2024-11-06
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024
8XGD
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BU of 8xgd by Molmil
Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in porcine brain lipids.
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, Gap junction delta-2 protein
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-15
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024
8XGE
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BU of 8xge by Molmil
Human Cx36/GJD2 gap junction channel in porcine brain lipids.
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-15
Release date:2024-11-06
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024
8XGF
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BU of 8xgf by Molmil
Human Cx36/GJD2 gap junction channel in complex with arachidonic acid.
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ARACHIDONIC ACID, Gap junction delta-2 protein
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-15
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024
8XH8
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BU of 8xh8 by Molmil
Human Cx36/GJD2 (Ala14-deleted mutant) gap junction channel in porcine brain lipids
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-17
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024
8XGG
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BU of 8xgg by Molmil
Human Cx36/GJD2 gap junction channel in complex with 1-hexanol.
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein, HEXAN-1-OL
Authors:Cho, H.J, Lee, H.H.
Deposit date:2023-12-15
Release date:2024-11-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer.
Nat Commun, 15, 2024

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