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PDB: 1 results

8FX5
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Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline
Descriptor: Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Vuckovic, Z, Mobbs, J.I, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M.
Deposit date:2023-01-23
Release date:2023-09-13
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Xanomeline displays concomitant orthosteric and allosteric binding modes at the M 4 mAChR.
Nat Commun, 14, 2023

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