PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 3
Descriptor:	ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
Authors:	Landel, I, Mueller, M.P, Rauh, D.
Deposit date:	2021-02-10
Release date:	2021-09-08
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nat Commun, 12, 2021

Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6
Descriptor:	ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide
Authors:	Landel, I, Mueller, M.P, Rauh, D.
Deposit date:	2021-02-10
Release date:	2021-09-08
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nat Commun, 12, 2021