9B1F
 
 | | Human urate transporter 1 URAT1 in apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12 | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1H
 | | Human urate transporter 1 URAT1 in complex with lesinurad | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, lesinurad | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1K
 | | Urate bound human URAT1 in the occluded state | | Descriptor: | Solute carrier family 22 member 12, URIC ACID | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1O
 | | Pyrazinoate bound human URAT1 in the inward-facing state (site3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12 | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1J
 | | Urate bound human URAT1 in the inward-facing state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Solute carrier family 22 member 12, ... | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1G
 | | Human urate transporter 1 URAT1 in complex with dotinurad | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, dotinurad | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1L
 | | Urate bound human URAT1 in the outward-facing state. | | Descriptor: | Solute carrier family 22 member 12, URIC ACID | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1N
 | | Pyrazinoate bound human URAT1 in the inward-facing state (site2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12 | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1I
 | | Human urate transporter 1 URAT1 in complex with verinurad | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, verinurad | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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9B1M
 | | Pyrazinoate bound human URAT1 in the inward-facing state (site1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PYRAZINE-2-CARBOXYLIC ACID, Solute carrier family 22 member 12 | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 34, 2024
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