9LNR
 
 | | Crystal structure of SKLB-D18 with ERK2 | | Descriptor: | 4-[5-chloranyl-2-[[3-[(dimethylamino)methyl]phenyl]amino]pyrimidin-4-yl]-~{N}-morpholin-4-yl-thiophene-2-carboxamide, GLYCEROL, Mitogen-activated protein kinase 1 | | Authors: | Xiao, H, Sun, Q. | | Deposit date: | 2025-01-21 | | Release date: | 2025-04-02 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A first-in-class selective inhibitor of ERK1/2 and ERK5 overcomes drug resistance with a single-molecule strategy.
Signal Transduct Target Ther, 10, 2025
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