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PDB: 2 results

4HTX
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BU of 4htx by Molmil
Crystal structure of PDE2 catalytic domain in complex with BAY60-7550
Descriptor: 2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one, MAGNESIUM ION, ZINC ION, ...
Authors:Zhu, J, Huang, Q.
Deposit date:2012-11-02
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc., 135, 2013
4HTZ
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BU of 4htz by Molmil
Crystal structure of PDE2 catalytic domain in space group P1
Descriptor: MAGNESIUM ION, ZINC ION, cGMP-dependent 3',5'-cyclic phosphodiesterase
Authors:Zhu, J, Huang, Q.
Deposit date:2012-11-02
Release date:2013-08-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc., 135, 2013

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