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PDB: 1 results

3RQD
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Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8
Descriptor: Histone deacetylase 8, Largazole, POTASSIUM ION, ...
Authors:Cole, K.E, Dowling, D.P, Christianson, D.W.
Deposit date:2011-04-28
Release date:2011-08-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.143 Å)
Cite:Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases.
J.Am.Chem.Soc., 133, 2011

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