PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

P38 in complex with Imatinib
Descriptor:	4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:	Namboodiri, H.V, Karpusas, M.
Deposit date:	2009-05-08
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry, 49, 2010

P38 in complex with Sorafenib
Descriptor:	4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Mitogen-activated protein kinase 14
Authors:	Namboodiri, H.V, Karpusas, M.
Deposit date:	2009-05-08
Release date:	2009-11-10
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry, 49, 2010