PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

PAK1 in complex with 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine
Descriptor:	2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine, MAGNESIUM ION, Serine/threonine-protein kinase PAK 1
Authors:	Gutmann, S, Rummel, G.
Deposit date:	2015-04-29
Release date:	2015-06-24
Last modified:	2015-07-29
Method:	X-RAY DIFFRACTION (1.99 Å)
Cite:	Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015

PAK1 in complex with (S)-N-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide
Descriptor:	(S)-N-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide, MAGNESIUM ION, Serine/threonine-protein kinase PAK 1
Authors:	Gutmann, S, Rummel, G.
Deposit date:	2015-04-29
Release date:	2015-06-24
Last modified:	2015-07-29
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015

Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1
Descriptor:	2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, GLYCEROL, Serine/threonine-protein kinase PAK 1
Authors:	Bellamacina, C.R, Bussiere, D.E.
Deposit date:	2015-05-01
Release date:	2015-08-05
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015