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Crystal structure of human kinesin Eg5 in complex with 3-(((2-Aminoethyl)sulfanyl)(3-ethylphenyl) phenylmethyl)phenol
Descriptor:	3-[(R)-2-azanylethylsulfanyl-(3-ethylphenyl)-phenyl-methyl]phenol, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:	Kaan, H.Y.K, Kozielski, F.
Deposit date:	2012-09-22
Release date:	2013-05-15
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Optimized S-Trityl-L-Cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models. J.Med.Chem., 56, 2013