PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Structure of Bace-1 (Beta-Secretase) in complex with N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide
Descriptor:	Beta-secretase 1, GLYCEROL, IODIDE ION, ...
Authors:	Sickmier, E.A.
Deposit date:	2012-02-22
Release date:	2012-10-10
Last modified:	2014-07-02
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase. ACS Med Chem Lett, 3, 2012

Structure of BACE Bound to (S)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor:	(6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, Beta-secretase 1, L(+)-TARTARIC ACID
Authors:	Strickland, C, Stamford, A.
Deposit date:	2012-06-26
Release date:	2012-10-10
Last modified:	2014-07-23
Method:	X-RAY DIFFRACTION (1.74 Å)
Cite:	A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of beta-Secretase. ACS Med Chem Lett, 3, 2012