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4KB9
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Crystal structure of wild-type HIV-1 protease with novel tricyclic P2-ligands GRL-0739A
Descriptor: (3aR,3bR,4S,7aR,8aS)-decahydrofuro[2,3-b][1]benzofuran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ...
Authors:Wang, Y.-F, Agniswamy, J, Weber, I.T.
Deposit date:2013-04-23
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Highly Potent HIV-1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein-Ligand X-ray Studies.
J.Med.Chem., 56, 2013

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