PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor E5E2
Descriptor:	Methylated Ruthenium Pyridocarbazole, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Authors:	Xie, P, Marmorstein, R.
Deposit date:	2008-04-10
Release date:	2008-05-20
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chem.Biol., 3, 2008

Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor DW2
Descriptor:	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, RU-PYRIDOCARBAZOLE-2
Authors:	Xie, P, Marmorstein, R.
Deposit date:	2008-04-09
Release date:	2008-05-27
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chem.Biol., 3, 2008