PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
Descriptor:	3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside, 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknA
Authors:	Zuccola, H.J.
Deposit date:	2017-09-20
Release date:	2018-02-14
Method:	X-RAY DIFFRACTION (2.88 Å)
Cite:	Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions. ACS Med Chem Lett, 8, 2017

Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
Descriptor:	5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknB
Authors:	Zuccola, H.J.
Deposit date:	2017-09-20
Release date:	2018-02-14
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (3.01 Å)
Cite:	Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions. ACS Med Chem Lett, 8, 2017