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PDB: 1 results

4ZK5
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BU of 4zk5 by Molmil
MAP4K4 in complex with inhibitor GNE-495
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 8-amino-N-[1-(cyclopropylcarbonyl)azetidin-3-yl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide, MAGNESIUM ION, ...
Authors:Harris, S.F, Wu, P, Coons, M.
Deposit date:2015-04-29
Release date:2015-09-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.
Acs Med.Chem.Lett., 6, 2015

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