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Crystal structure of the VHL-EloC-EloB complex with a covalent compound bound to C77 of VHL.
Descriptor:	Elongin-B, Isoform 2 of Elongin-C, N-[2-(dimethylsulfamoyl)-5-[(1-methylpyrazol-4-yl)methoxy]phenyl]propanamide, ...
Authors:	Collie, G.W.
Deposit date:	2024-08-19
Release date:	2025-03-26
Last modified:	2025-04-30
Method:	X-RAY DIFFRACTION (1.486 Å)
Cite:	Discovery of a Series of Covalent Ligands That Bind to Cys77 of the Von Hippel-Lindau Tumor Suppressor Protein (VHL). Acs Med.Chem.Lett., 16, 2025