9DAQ
 
 | Structure of E. coli dihydrofolate reductase (DHFR) in an occluded conformation and in complex with a cycloguanil derivative | Descriptor: | (6S)-1-(4-chlorophenyl)-6-ethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, Dihydrofolate reductase | Authors: | Berkovich, D.A, Jez, J.M. | Deposit date: | 2024-08-22 | Release date: | 2025-02-26 | Last modified: | 2025-03-26 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Expanding the Landscape of Dual Action Antifolate Antibacterials through 2,4-Diamino-1,6-dihydro-1,3,5-triazines. Acs Infect Dis., 11, 2025
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9DAR
 
 | Structure of E. coli dihydrofolate reductase (DHFR) in an occluded conformation and in complex with cycloguanil | Descriptor: | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, CITRATE ANION, Dihydrofolate reductase | Authors: | Berkovich, D.A, Jez, J.M. | Deposit date: | 2024-08-22 | Release date: | 2025-02-26 | Last modified: | 2025-03-26 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Expanding the Landscape of Dual Action Antifolate Antibacterials through 2,4-Diamino-1,6-dihydro-1,3,5-triazines. Acs Infect Dis., 11, 2025
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