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From DNA-Encoded Library Screening to AM-9747 - an MTA-Cooperative PRMT5 Inhibitor with Potent Oral in vivo Efficacy
Descriptor:	2-amino-3-methyl-N-[(1R)-1-(pyrimidin-2-yl)ethyl]-N-{[5-(trifluoromethyl)pyridin-2-yl]methyl}quinoline-6-carboxamide, 5'-DEOXY-5'-METHYLTHIOADENOSINE, DI(HYDROXYETHYL)ETHER, ...
Authors:	GhimireRijal, S, Mukund, S.
Deposit date:	2025-01-07
Release date:	2025-03-26
Last modified:	2025-04-02
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	From DNA-Encoded Library Screening to AM-9747 : An MTA-Cooperative PRMT5 Inhibitor with Potent Oral In Vivo Efficacy. J.Med.Chem., 68, 2025