9E5F
 
 | | Discovery of an Orally Bioavailable KRAS G12D Inhibitor | | Descriptor: | (4P)-4-{1-[(1R,4R,5S)-2-azabicyclo[2.1.1]hexan-5-yl]-8-chloro-4-[3-(dimethylamino)azetidin-1-yl]-6-fluoro-1H-imidazo[4,5-c]quinolin-7-yl}naphthalen-2-ol, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Deller, M.C, Epling, L.B. | | Deposit date: | 2024-10-28 | | Release date: | 2025-01-22 | | Last modified: | 2025-02-05 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor.
J.Med.Chem., 68, 2025
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9E5D
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