9GU4
 
 | | Crystal structure of NLRP3 in complex with inhibitor NP3-253 | | Descriptor: | 2-[6-[[(3R)-1-ethylpiperidin-3-yl]amino]pyridazin-3-yl]-3-methyl-5-(trifluoromethyl)phenol, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... | | Authors: | Srinivas, H. | | Deposit date: | 2024-09-18 | | Release date: | 2024-12-11 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (2.696 Å) | | Cite: | Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome.
J.Med.Chem., 67, 2024
|
|
