8RGF
 
 | | Arginase 2 in complex with inhibitor | | Descriptor: | 4-[(2~{R},4~{R})-4-azanyl-2-carboxy-pyrrolidin-2-yl]butyl-tris(oxidanyl)boranuide, Arginase-2, mitochondrial, ... | | Authors: | Petersen, J. | | Deposit date: | 2023-12-13 | | Release date: | 2024-12-04 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Discovery of (2 R ,4 R )-4-(( S )-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
J.Med.Chem., 67, 2024
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8RGU
 | | Arginase 2 in complex with inhibitor | | Descriptor: | Arginase-2, mitochondrial, DIMETHYL SULFOXIDE, ... | | Authors: | Petersen, J. | | Deposit date: | 2023-12-14 | | Release date: | 2024-12-04 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of (2 R ,4 R )-4-(( S )-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
J.Med.Chem., 67, 2024
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8RG6
 | | Arginase 2 in complex with inhibitor | | Descriptor: | (2~{S},3~{R})-3-[3-(dihydroxyboranyl)propyl]pyrrolidine-2-carboxylic acid, Arginase-2, mitochondrial, ... | | Authors: | Petersen, J. | | Deposit date: | 2023-12-13 | | Release date: | 2024-12-04 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Discovery of (2 R ,4 R )-4-(( S )-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
J.Med.Chem., 67, 2024
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8RFA
 | | Arginase 2 in complex with an inhibitor | | Descriptor: | Arginase-2, mitochondrial, MANGANESE (II) ION, ... | | Authors: | Petersen, J. | | Deposit date: | 2023-12-12 | | Release date: | 2024-11-27 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Discovery of (2 R ,4 R )-4-(( S )-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
J.Med.Chem., 67, 2024
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