PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

MerTK in complex with small molecule 6-{1-[([1,1'-biphenyl]-4-yl)carbamoyl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide
Descriptor:	6-{1-[([1,1'-biphenyl]-4-yl)carbamoyl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
Authors:	Jakob, C.G, Qiu, W.
Deposit date:	2024-04-20
Release date:	2024-10-09
Method:	X-RAY DIFFRACTION (2.294 Å)
Cite:	Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement. J.Med.Chem., 2024

MerTK in complex with small molecule inhibitor 6-{1-[6-(3-hydroxy-3-methylbutoxy)-1,3-benzoxazol-2-yl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide
Descriptor:	6-{1-[6-(3-hydroxy-3-methylbutoxy)-1,3-benzoxazol-2-yl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
Authors:	Jakob, C.G, Gurbani, D, Qiu, W.
Deposit date:	2024-04-20
Release date:	2024-10-09
Method:	X-RAY DIFFRACTION (2.106 Å)
Cite:	Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement. J.Med.Chem., 2024