8UQH
 
 | | X-ray crystal structure of PRMT4 bound to compound YD-1130 | | Descriptor: | 5'-S-(2-{[(3-bromophenyl)methyl]amino}ethyl)-5'-thioadenosine, Histone-arginine methyltransferase CARM1 | | Authors: | Bush, M, Noinaj, N, Deng, Y, Huang, R. | | Deposit date: | 2023-10-23 | | Release date: | 2025-04-02 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | An Adenosine Analogue Library Reveals Insights into Active Sites of Protein Arginine Methyltransferases and Enables the Discovery of a Selective PRMT4 Inhibitor.
J.Med.Chem., 67, 2024
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