PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal Structure of PDE10A with a biaryl ether inhibitor (1-(1-(3-(4-(benzo[d]thiazol-2-ylamino)phenoxy)pyrazin-2-yl)piperidin-4-yl)ethanol)
Descriptor:	(1S)-1-(1-{3-[4-(1,3-benzothiazol-2-ylamino)phenoxy]pyrazin-2-yl}piperidin-4-yl)ethanol, GLYCEROL, SULFATE ION, ...
Authors:	Chmait, S, Jordan, S.
Deposit date:	2012-10-04
Release date:	2012-12-12
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux. Bioorg.Med.Chem.Lett., 22, 2012

Crystal Structure of PDE10A with a biaryl ether inhibitor ((1-(3-(4-((1H-benzo[d]imidazol-2-yl)amino)phenoxy)pyridin-2-yl)piperidin-4-yl)methanol)
Descriptor:	(1-{3-[4-(1H-benzimidazol-2-ylamino)phenoxy]pyridin-2-yl}piperidin-4-yl)methanol, SULFATE ION, ZINC ION, ...
Authors:	Chmait, S, Jordan, S.
Deposit date:	2012-10-04
Release date:	2012-12-12
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux. Bioorg.Med.Chem.Lett., 22, 2012