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P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor
Descriptor:	1-[2-(2-{[2-(dimethylamino)ethyl]amino}-6-{2-[(1-methylethyl)amino]-1,3-thiazol-5-yl}pyrimidin-4-yl)benzyl]-3-ethylurea, Mitogen-activated protein kinase 14
Authors:	Sack, J.S.
Deposit date:	2010-07-12
Release date:	2010-09-08
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38alpha MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010