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Crystal Structure of the human mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgADP
Descriptor:	5-acetyl-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ...
Authors:	Dougan, D.R, Mol, C.D.
Deposit date:	2010-03-25
Release date:	2010-07-28
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors. Bioorg.Med.Chem.Lett., 20, 2010