9JXF
 
 | | Cryo-EM structure of apo human XPR1, class 2, with asymmetrically dimerized SPX domains | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (4.31 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXG
 | | Cryo-EM structure of apo human XPR1, class 3, with symmetrically dimerized SPX domains | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXH
 | | Cryo-EM structure of human XPR1 in complex with InsP8 | | Descriptor: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXI
 | | Cryo-EM structure of human XPR1 with InsP8 in an 'arch-like' intermediate state of the SPX domain | | Descriptor: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXJ
 | | Cryo-EM structure of human XPR1 in a closed state at both the extracellular and intracellular gates, obtained through local refinement | | Descriptor: | PHOSPHATE ION, Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXL
 | | Cryo-EM structure of human XPR1 in an open state at the intracellular gate and a closed state at the extracellular gate, obtained through local refinement | | Descriptor: | PHOSPHATE ION, Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXK
 | | Cryo-EM structure of human XPR1 in a closed state at the intracellular gate and an open state at the extracellular gate, obtained through local refinement | | Descriptor: | PHOSPHATE ION, Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXM
 | | Cryo-EM structure of one subunit of the human XPR1 homodimer with both the intracellular and extracellular gates in an open state, obtained through local refinement | | Descriptor: | PHOSPHATE ION, Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXP
 | | Cryo-EM structure of human XPR1-R570L | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXO
 | | Cryo-EM structure of human XPR1-G621A | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXQ
 | | Complex of XPR1-KIDINS220 | | Descriptor: | Kinase D-interacting substrate of 220 kDa, Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXE
 | | Cryo-EM structure of apo human XPR1, class 1, with one visible SPX domain | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXR
 | | Cryo-EM structure of Drosophila melanogaster PXo-G604A | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXD
 | | Cryo-EM structure of human XPR1 in apo state | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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9JXN
 | | Cryo-EM structure of human XPR1-R459C | | Descriptor: | Solute carrier family 53 member 1 | | Authors: | Wang, X, Bai, Z, Wallis, C, Wang, H, Han, Y, Jin, R, Lei, M, Gu, C, Jessen, H, Shears, S, Sun, Y, Corry, B, Zhang, Y. | | Deposit date: | 2024-10-11 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM structure of human XPR1 in apo state
Mol.Cell, 2025
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