PDB Search results for query - Protein Data Bank Japan

PDB: 1 results

Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor TK-453
Descriptor:	6-[4-(aminomethyl)-4-methyl-piperidin-1-yl]-3-[2,3-bis(chloranyl)phenyl]sulfanyl-pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11
Authors:	Li, T.H, Guo, H.T, Ji, X.Y.
Deposit date:	2021-11-12
Release date:	2022-03-23
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis. Iscience, 25, 2022