9H0Y
 
 | | ProA in complex with inhibitor 7 | | Descriptor: | (R,R)-2,3-BUTANEDIOL, GLYCEROL, SULFATE ION, ... | | Authors: | Ornago, C, Blankenfeldt, W. | | Deposit date: | 2024-10-09 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Innovative zinc-binding inhibitors of Legionella pneumophila ProA reduce collagen and flagellin degradation, TLR5 evasion, and human lung tissue inflammation.
Eur.J.Med.Chem., 296, 2025
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9H0X
 | | ProA in complex with inhibitor 6 | | Descriptor: | (2~{R})-2-(2-methylpropyl)-~{N}-[4-[[4-[(2-methylpropylsulfonylamino)methyl]-1,2,3-triazol-1-yl]methyl]phenyl]-~{N}'-oxidanyl-propanediamide, ZINC ION, Zinc metalloproteinase | | Authors: | Ornago, C, Blankenfeldt, W. | | Deposit date: | 2024-10-09 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Innovative zinc-binding inhibitors of Legionella pneumophila ProA reduce collagen and flagellin degradation, TLR5 evasion, and human lung tissue inflammation.
Eur.J.Med.Chem., 296, 2025
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