9JDU
 
 | | The crystal structure of PDE10A complexed with inhibitor 2061 | | Descriptor: | MAGNESIUM ION, ZINC ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ... | | Authors: | Huang, Y.-Y, Guo, L, Luo, H.-B. | | Deposit date: | 2024-09-01 | | Release date: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2.3000176 Å) | | Cite: | Discovery of novel azetidine-based imidazopyridines as selective and orally bioavailable inhibitors of phosphodiesterase 10A for the treatment of pulmonary arterial hypertension.
Eur.J.Med.Chem., 290, 2025
|
|
