PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Crystal structure of the HECT domain of Smurf 2 in complex with inhibitor 8
Descriptor:	E3 ubiquitin-protein ligase SMURF2, PHOSPHATE ION, ethyl 5-[1,3-benzodioxol-5-ylmethyl(ethyl)carbamoyl]-2,4-dimethyl-1~{H}-pyrrole-3-carboxylate
Authors:	Ostermann, N.
Deposit date:	2024-06-21
Release date:	2025-04-16
Last modified:	2025-05-28
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	Therapeutic potential of allosteric HECT E3 ligase inhibition. Cell, 188, 2025

Crystal structure of the HECT domain of Smurf 1 in complex with inhibitor 8
Descriptor:	E3 ubiquitin-protein ligase SMURF1, ethyl 5-[1,3-benzodioxol-5-ylmethyl(ethyl)carbamoyl]-2,4-dimethyl-1~{H}-pyrrole-3-carboxylate
Authors:	Ostermann, N.
Deposit date:	2024-06-21
Release date:	2025-04-16
Last modified:	2025-05-28
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Therapeutic potential of allosteric HECT E3 ligase inhibition. Cell, 188, 2025

Crystal structure of the HECT domain of Smurf1
Descriptor:	E3 ubiquitin-protein ligase SMURF1
Authors:	Ostermann, N.
Deposit date:	2024-06-21
Release date:	2025-04-16
Last modified:	2025-05-28
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Therapeutic potential of allosteric HECT E3 ligase inhibition. Cell, 188, 2025