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Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea]
Descriptor:	JTO light chain, N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea, PHOSPHATE ION
Authors:	Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:	2021-08-13
Release date:	2022-02-16
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg.Med.Chem.Lett., 60, 2022