PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Structure of a hit for G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure
Descriptor:	3-benzyl-7-(1H-pyrazol-4-yl)quinazolin-4(3H)-one, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:	Spurlino, J.C, Milligan, C.
Deposit date:	2020-09-24
Release date:	2020-10-28
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.606087 Å)
Cite:	Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor. Bioorg.Med.Chem.Lett., 30, 2020

Structure of a hit for G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure
Descriptor:	3-benzyl-6-(1H-pyrazol-4-yl)quinazolin-4(3H)-one, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:	Spurlino, J.C, Milligan, C.
Deposit date:	2020-09-23
Release date:	2020-10-28
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.539 Å)
Cite:	Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor. Bioorg.Med.Chem.Lett., 30, 2020