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Structure of Bace-1 (Beta-Secretase) in complex with : N-(3-((1R,5S,6R)-3-amino-5-methyl-2-oxa-4-azabicyclo[4.1.0]hept-3-en-5-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
Descriptor:	Beta-secretase 1, GLYCEROL, IODIDE ION, ...
Authors:	Sickmier, E.A.
Deposit date:	2018-01-08
Release date:	2018-02-21
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Diastereoselective synthesis of fused cyclopropyl-3-amino-2,4-oxazine beta-amyloid cleaving enzyme (BACE) inhibitors and their biological evaluation. Bioorg. Med. Chem. Lett., 28, 2018