PDB Search results for query - Protein Data Bank Japan

PDB: 1 results

Bace1 in complex with the aminohydantoin Compound 102
Descriptor:	(5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[4-fluoro-3-(5-fluoropent-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1
Authors:	Olland, A.M.
Deposit date:	2010-08-31
Release date:	2011-08-31
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Design and Synthesis of Aminohydantoins as Potent and Selective Human beta-Secretase (BACE1) Inhibitors with Enhanced Brain Permeability Bioorg.Med.Chem.Lett., 20, 2010