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PDB: 1 results

Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
Descriptor:	3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase
Authors:	Harris, S.F, Tavares, G, Ghate, M.
Deposit date:	2010-04-01
Release date:	2010-07-28
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010