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PDB: 1 results
3ITZ
Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor
Descriptor:
4-chloro-N-cyclopropyl-3-{[1-(2,6-difluorophenyl)-1H-pyrazolo[3,4-d]pyridazin-4-yl]amino}benzamide, Mitogen-activated protein kinase 14
Authors:
Mohr, C
,
Jordan, S.
Deposit date:
2009-08-28
Release date:
2010-03-02
Last modified:
2024-02-21
Method:
X-RAY DIFFRACTION (2.25 Å)
Cite:
Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.
Bioorg.Med.Chem.Lett., 20, 2010
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数据于2024-05-15公开中