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PDB: 1 results

B-Raf wild-type kinase domain in complex with a purinylpyridinylamino-based inhibitor
Descriptor:	6-[2-[[3-(dimethylsulfamoylamino)-2,6-bis(fluoranyl)phenyl]amino]pyridin-3-yl]-7~{H}-purine, Serine/threonine-protein kinase B-raf
Authors:	Whittington, D.A, Epstein, L.F.
Deposit date:	2015-12-15
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.89 Å)
Cite:	Purinylpyridinylamino-based DFG-in/ alpha C-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling. Bioorg.Med.Chem., 24, 2016