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PDB: 3 results

8QY9
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BU of 8qy9 by Molmil
J22.9-H, fully humanized Fab Fragment based on chimeric J22.9-xi IgG against BCMA
Descriptor: COPPER (II) ION, Fab heavy chain of J22.9-H, Fab light chain of J22.9-H, ...
Authors:Marino, S.F, Daumke, O.
Deposit date:2023-10-25
Release date:2024-01-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based humanization of a therapeutic antibody for multiple myeloma.
J.Mol.Med., 102, 2024
8QYA
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BU of 8qya by Molmil
J22.9-FNY, fully humanized, CDR optimized Fab Fragment based on chimeric J22.9-xi IgG against BCMA; with VH CDR2 glycosylation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, J22.9-FNY Fab antibody heavy chain, ...
Authors:Marino, S.F, Daumke, O.
Deposit date:2023-10-25
Release date:2024-01-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structure-based humanization of a therapeutic antibody for multiple myeloma.
J.Mol.Med., 102, 2024
8QYB
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BU of 8qyb by Molmil
J22.9-ISY, fully humanized and CDR optimized Fab Fragment based on chimeric J22.9-xi IgG against BCMA
Descriptor: COPPER (II) ION, Fab heavy chain of J22.9-ISY, Fab light chain of J22.9-ISY, ...
Authors:Marino, S.F, Daumke, O.
Deposit date:2023-10-25
Release date:2024-01-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structure-based humanization of a therapeutic antibody for multiple myeloma.
J.Mol.Med., 102, 2024

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