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PDB: 14 results

8PBG
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BU of 8pbg by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBP
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BU of 8pbp by Molmil
Mutant R1785C of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBE
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BU of 8pbe by Molmil
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBI
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BU of 8pbi by Molmil
Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBM
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BU of 8pbm by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBQ
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BU of 8pbq by Molmil
Mutant R1810Q of the dihydroorotase domain of human CAD protein bound to the substrates
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBR
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BU of 8pbr by Molmil
Mutant R1475Q of the dihydroorotase domain of human CAD protein in apo form
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBJ
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BU of 8pbj by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, GLYCEROL, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBN
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BU of 8pbn by Molmil
Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBT
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BU of 8pbt by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBU
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BU of 8pbu by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBH
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BU of 8pbh by Molmil
Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBK
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BU of 8pbk by Molmil
Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023
8PBS
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BU of 8pbs by Molmil
Mutant K1482M of the dihydroorotase domain of human CAD protein in apo form
Descriptor: CAD protein, FORMIC ACID, GLYCEROL, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2023-06-09
Release date:2023-11-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
J Inherit Metab Dis, 46, 2023

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