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PDB: 1 results

Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7
Descriptor:	(9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:	Molodtsov, V, Ebright, R.H.
Deposit date:	2022-02-22
Release date:	2022-10-19
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (3.87 Å)
Cite:	Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl., 61, 2022