8OGJ
| Structure of Candida albicans 80S ribosome in complex with mefloquine | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | Authors: | Kolosova, O, Zgadzay, Y, Stetsenko, A, Guskov, A, Yusupov, M. | Deposit date: | 2023-03-20 | Release date: | 2024-10-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement To Be Published
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8OH6
| Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (500umol) | Descriptor: | 18S, 25S (gene name XR_002086444.1), 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | Deposit date: | 2023-03-20 | Release date: | 2024-10-02 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement To Be Published
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8QK7
| E167K RF2 on E. coli 70S release complex with UAA | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | Deposit date: | 2023-09-14 | Release date: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria To Be Published
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8OEQ
| Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (250uM) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | Deposit date: | 2023-03-12 | Release date: | 2024-09-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement To Be Published
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9AX8
| 70S initiation complex (tRNA-fMet M1, initiation factor 2 + CUG start codon) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Mattingly, J.M, Nguyen, H.A, Dunham, C.M. | Deposit date: | 2024-03-06 | Release date: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural analysis of noncanonical translation initiation complexes. J.Biol.Chem., 2024
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9AX7
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9CG7
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9CG6
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9CG5
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8CRE
| Crystal structure of the Candida albicans 80S ribosome in complex with geneticin G418 | Descriptor: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | Deposit date: | 2023-03-08 | Release date: | 2024-09-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement To Be Published
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8CQW
| Crystal structure of the Candida albicans 80S ribosome in complex with Hygromycin B | Descriptor: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | Deposit date: | 2023-03-07 | Release date: | 2024-09-18 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement To Be Published
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9CAI
| High-resolution C. elegans 80S ribosome structure - class 1 | Descriptor: | 18S rRNA, 28S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | Authors: | Sehgal, E, Serrao, V.H.B, Arribere, J. | Deposit date: | 2024-06-17 | Release date: | 2024-09-11 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | High-Resolution Reconstruction of a C. elegans Ribosome Sheds Light on Evolutionary Dynamics and Tissue Specificity. Rna, 2024
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8S8H
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2.2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8D
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8G
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2.1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8RW1
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-02-02 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8E
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-3.1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8F
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-3.2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8J
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF5) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8I
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8CQ7
| Crystal structure of phyllanthoside bound to the Candida albicans 80S ribosome | Descriptor: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | Authors: | Kolosova, O, Zgadzay, Y, Yusupov, M. | Deposit date: | 2023-03-03 | Release date: | 2024-09-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement To Be Published
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9BLN
| The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex | Descriptor: | 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... | Authors: | Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C. | Deposit date: | 2024-04-30 | Release date: | 2024-09-04 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun, 15, 2024
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9BKD
| The structure of human Pdcd4 bound to the 40S small ribosomal subunit | Descriptor: | 18S rRNA, 40S ribosomal protein S12, 40S ribosomal protein S13, ... | Authors: | Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Albacete-Albacete, L, Ramakrishnan, V, S.Fraser, C. | Deposit date: | 2024-04-27 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun, 15, 2024
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9BH5
| High-resolution C. elegans 80S ribosome structure - class 1 | Descriptor: | 18S rRNA, 28S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | Authors: | Sehgal, E, Serrao, V.H.B, Arribere, J. | Deposit date: | 2024-04-19 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | High-Resolution Reconstruction of a C. elegans Ribosome Sheds Light on Evolutionary Dynamics and Tissue Specificity. Rna, 2024
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8Q7Z
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