5IRR
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![BU of 5irr by Molmil](/molmil-images/mine/5irr) | Crystal structure of Septin GTPase domain from Chlamydomonas reinhardtii | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Septin-like protein | Authors: | Pinto, A.P.A, Pereira, H.M, Navarro, M.V.A.S, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U. | Deposit date: | 2016-03-14 | Release date: | 2017-04-26 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii. J. Biol. Chem., 292, 2017
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8DKT
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![BU of 8dkt by Molmil](/molmil-images/mine/8dkt) | Crystal Structure of Septin1 - Septin2 heterocomplex from Drosophila melanogaster | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | de Freitas, A.F, Leonardo, D.A, Cavini, I.A, Pereira, H.M, Garratt, R.C. | Deposit date: | 2022-07-06 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Conservation and divergence of the G-interfaces of Drosophila melanogaster septins. Cytoskeleton (Hoboken), 80, 2023
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3FTQ
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![BU of 3ftq by Molmil](/molmil-images/mine/3ftq) | |
8FWP
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![BU of 8fwp by Molmil](/molmil-images/mine/8fwp) | Crystal Structure of CDC10 - CDC3 heterocomplex from Saccharomyces cerevisiae | Descriptor: | Cell division control protein 10, Cell division control protein 3, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Silva, R.M, Leonardo, D.A, Pereira, H.M, Garratt, R.C. | Deposit date: | 2023-01-23 | Release date: | 2023-07-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly. J.Struct.Biol., 215, 2023
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7M6J
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![BU of 7m6j by Molmil](/molmil-images/mine/7m6j) | Human Septin Hexameric Complex SEPT2G/SEPT6/SEPT7 by Single Particle Cryo-EM | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mendonca, D.C, Pereira, H.M, van Heel, M, Portugal, R.V, Garratt, R.C. | Deposit date: | 2021-03-25 | Release date: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | An atomic model for the human septin hexamer by cryo-EM. J.Mol.Biol., 433, 2021
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9BHT
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![BU of 9bht by Molmil](/molmil-images/mine/9bht) | Septin Hexameric Complex SEPT2/SEPT6/SEPT7 of Ciona intestinalis by Cryo-EM | Descriptor: | CiSeptin-2, CiSeptin-6, CiSeptin-7, ... | Authors: | Mendonca, D.C, Pereira, H.M, Garratt, R.C. | Deposit date: | 2024-04-22 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural Insights into Ciona intestinalis Septins: Complexes Suggest a Mechanism for Nucleotide-dependent Interfacial Cross-talk. J.Mol.Biol., 436, 2024
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9BHW
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4KVA
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![BU of 4kva by Molmil](/molmil-images/mine/4kva) | GTPase domain of Septin 10 from Schistosoma mansoni in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Septin | Authors: | Zeraik, A.E, Pereira, H.M, Santos, Y.V, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U, Demarco, R. | Deposit date: | 2013-05-22 | Release date: | 2014-02-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Crystal Structure of a Schistosoma mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide. J.Biol.Chem., 289, 2014
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4KV9
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![BU of 4kv9 by Molmil](/molmil-images/mine/4kv9) | GTPase domain of Septin 10 from Schistosoma mansoni in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Septin | Authors: | Zeraik, A.E, Pereira, H.M, Santos, Y.V, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U, Demarco, R. | Deposit date: | 2013-05-22 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal Structure of a Schistosoma mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide. J.Biol.Chem., 289, 2014
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8PFH
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![BU of 8pfh by Molmil](/molmil-images/mine/8pfh) | Crystal structure of the yeast septin complex Shs1-Cdc12-Cdc3-Cdc10 | Descriptor: | CDC10 isoform 1, CDC12 isoform 1, Cell division control protein 3, ... | Authors: | Grupp, B, Denkhaus, L, Gerhardt, S, Gronemeyer, T. | Deposit date: | 2023-06-16 | Release date: | 2023-12-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity. Commun Biol, 7, 2024
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8SGD
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![BU of 8sgd by Molmil](/molmil-images/mine/8sgd) | Crystal Structure of CDC3(G) - CDC10(Delta 1-10) heterocomplex from Saccharomyces cerevisiae | Descriptor: | CDC10 isoform 1, CDC3 isoform 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Saladino, G.C.R, Leonardo, D.A, Pereira, H.M, Garratt, R.C. | Deposit date: | 2023-04-12 | Release date: | 2023-06-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly. J.Struct.Biol., 215, 2023
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5AR1
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![BU of 5ar1 by Molmil](/molmil-images/mine/5ar1) | Crystal structure of Cdc11 from Saccharomyces cerevisiae | Descriptor: | CELL DIVISION CONTROL PROTEIN 11 | Authors: | Brausemann, A, Gerhardt, S, Schott, A.K, Einsle, O, Grosse-Berkenbusch, A, Johnsson, N, Gronemeyer, T. | Deposit date: | 2015-09-23 | Release date: | 2016-01-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure of Cdc11, a Septin Subunit from Saccharomyces Cerevisiae. J.Struct.Biol., 193, 2016
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4YQF
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![BU of 4yqf by Molmil](/molmil-images/mine/4yqf) | GTPase domain of Human Septin 9 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-9 | Authors: | Matos, S.O, Leonardo, D.A, Macedo, J.N, Pereira, H.M, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2015-03-13 | Release date: | 2016-03-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | GTPase domain of Human Septin 9 To Be Published
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3T5D
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![BU of 3t5d by Molmil](/molmil-images/mine/3t5d) | |
5CYP
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![BU of 5cyp by Molmil](/molmil-images/mine/5cyp) | GTPase domain of Septin 9 in complex with GTP-gamma-S | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Septin-9 | Authors: | Matos, S.S, Leonardo, D.A, Pereira, H.M, Horjales, E, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2015-07-30 | Release date: | 2016-08-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.893 Å) | Cite: | A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface Iucrj, 2020
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3SOP
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![BU of 3sop by Molmil](/molmil-images/mine/3sop) | Crystal Structure Of Human Septin 3 GTPase Domain | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Neuronal-specific septin-3 | Authors: | Marques, I.A, Macedo, J.N.A, Pereira, H.M, Valadares, N.F, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2011-06-30 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.885 Å) | Cite: | The structure and properties of septin 3: a possible missing link in septin filament formation. Biochem.J., 450, 2013
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5CYO
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![BU of 5cyo by Molmil](/molmil-images/mine/5cyo) | High resolution Septin 9 GTPase domain in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-9 | Authors: | Matos, S.S, Leonardo, D.A, Pereira, H.M, Horjales, E, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2015-07-30 | Release date: | 2016-08-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.0354 Å) | Cite: | A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface Iucrj, 2020
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4Z51
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![BU of 4z51 by Molmil](/molmil-images/mine/4z51) | High Resolution Human Septin 3 GTPase domain | Descriptor: | MAGNESIUM ION, Neuronal-specific septin-3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Valadares, N.F, Macedo, J.N, Leonardo, D.A, Brandao-Neto, J, Pereira, H.M, Matos, S.O, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2015-04-02 | Release date: | 2016-04-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface Iucrj, 2020
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4Z54
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![BU of 4z54 by Molmil](/molmil-images/mine/4z54) | High Resolution Human Septin3 GTPase domain with alpha-zero helix in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Neuronal-specific septin-3 | Authors: | Valadares, N.F, Macedo, J.N, Pereira, H.M, Brandao-Neto, J, Matos, S.O, Leonardo, D.A, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2015-04-02 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface Iucrj, 2020
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2QA5
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![BU of 2qa5 by Molmil](/molmil-images/mine/2qa5) | |
2QNR
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![BU of 2qnr by Molmil](/molmil-images/mine/2qnr) | Human septin 2 in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Septin-2, UNKNOWN ATOM OR ION | Authors: | Rabeh, W.M, Nedyalkova, L, Tempel, W, Landry, R, Crombet, L, Kozieradzki, I, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2007-07-19 | Release date: | 2007-07-31 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Human septin 2 in complex with GDP. To be Published
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2QAG
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![BU of 2qag by Molmil](/molmil-images/mine/2qag) | Crystal structure of human septin trimer 2/6/7 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Septin-2, ... | Authors: | Sirajuddin, M. | Deposit date: | 2007-06-15 | Release date: | 2007-08-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural insight into filament formation by mammalian septins. Nature, 449, 2007
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3TW4
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![BU of 3tw4 by Molmil](/molmil-images/mine/3tw4) | Crystal Structure of Human Septin 7 GTPase Domain | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Septin-7 | Authors: | Serrao, V.H.B, Alessandro, F, Pereira, H.M, Thiemann, O.T, Garratt, R.C. | Deposit date: | 2011-09-21 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Promiscuous interactions of human septins: The GTP binding domain of SEPT7 forms filaments within the crystal. Febs Lett., 585, 2011
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6UPR
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![BU of 6upr by Molmil](/molmil-images/mine/6upr) | Crystal Structure of GTPase Domain of Human Septin 2 / Septin 8 Heterocomplex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Leonardo, D.A, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2019-10-18 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Molecular Recognition at Septin Interfaces: The Switches Hold the Key. J.Mol.Biol., 432, 2020
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6UQQ
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![BU of 6uqq by Molmil](/molmil-images/mine/6uqq) | Crystal Structure of GTPase Domain of Human Septin 7 / Septin 3 T282Y Heterocomplex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Neuronal-specific septin-3, Septin-7 | Authors: | Bragnara, G, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C. | Deposit date: | 2019-10-21 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Molecular Recognition at Septin Interfaces: The Switches Hold the Key. J.Mol.Biol., 432, 2020
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