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4DN4
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BU of 4dn4 by Molmil
Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a
Descriptor: ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ...
Authors:Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
3TN2
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BU of 3tn2 by Molmil
structure analysis of MIP1-beta P8A
Descriptor: C-C motif chemokine 4, ZINC ION
Authors:Guo, Q, Tang, W.J.
Deposit date:2011-09-01
Release date:2012-09-05
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
6FGP
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BU of 6fgp by Molmil
NMR solution structure of monomeric CCL5 in complex with a doubly-sulfated N-terminal segment of CCR5
Descriptor: C-C chemokine receptor type 5, C-C motif chemokine 5
Authors:Anglister, J, Abayev, M.
Deposit date:2018-01-11
Release date:2018-04-18
Last modified:2022-03-30
Method:SOLUTION NMR
Cite:The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5.
FEBS J., 285, 2018
6N2U
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BU of 6n2u by Molmil
IL-8 Structure from Bacterial Expression Source
Descriptor: Interleukin-8
Authors:Park, H, Jung, J.H, Luo, J.L.
Deposit date:2018-11-14
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.254 Å)
Cite:IL-8 Structure from Bacterial Expression Source
To Be Published
1ZXT
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BU of 1zxt by Molmil
Crystal Structure of A Viral Chemokine
Descriptor: functional macrophage inflammatory protein 1-alpha homolog
Authors:Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A.
Deposit date:2005-06-08
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
5OB5
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BU of 5ob5 by Molmil
fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
Descriptor: C-X-C motif chemokine 2, GLYCEROL, SULFATE ION, ...
Authors:Zhao, B, Ward, P, Convery, M.A.
Deposit date:2017-06-26
Release date:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery
To Be Published
6SHR
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BU of 6shr by Molmil
X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A
Descriptor: Stromal cell-derived factor 1
Authors:Jugnarain, V.M, Mitchell, E, Forsyth, T, Michael, H, Cortes, S, Tillier, B.
Deposit date:2019-08-08
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.745 Å)
Cite:X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A
To Be Published
3KBX
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BU of 3kbx by Molmil
Human macrophage inflammatory protein-1 alpha L3M_V63M
Descriptor: ACETATE ION, CCL3, POTASSIUM ION
Authors:Guo, Q, Ren, M, Tang, W.-J.
Deposit date:2009-10-20
Release date:2010-10-27
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.652 Å)
Cite:Structural basis for the oligomerization of macrophage inflammatory protein-1 alpha
To be Published
6STK
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BU of 6stk by Molmil
Crystal structure of the CC-chemokine 5 (CCL5) E66S mutation
Descriptor: ACETATE ION, C-C motif chemokine 5, GLYCEROL
Authors:Ramirez-Escudero, M, Janssen, B.J.C.
Deposit date:2019-09-10
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4.
J.Biol.Chem., 295, 2020
1HA6
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BU of 1ha6 by Molmil
NMR Solution Structure of Murine CCL20/MIP-3a Chemokine
Descriptor: MACROPHAGE INFLAMMATORY PROTEIN 3 ALPHA
Authors:Perez-Canadillas, J.M, Zaballos, A, Gutierrez, J, Varona, R, Roncal, F, Albar, J.P, Marquez, G, Bruix, M.
Deposit date:2001-03-28
Release date:2001-08-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of Murine Ccl20/Mip3-A, a Chemiokine that Specifically Chemoattracs Immature Dendritic Cells and Lymphocytes Through its Highly Specific Interaction with the Beta-Chemokine Receptor Ccr6
J.Biol.Chem., 276, 2001
1HFN
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BU of 1hfn by Molmil
NMR solution structures of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus.
Descriptor: VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Authors:Crump, M.P, Elisseeva, E, Gong, J.-H, Clark-Lewis, I, Sykes, B.D.
Deposit date:2000-12-07
Release date:2001-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure/Function of Human Herpesvirus-8 Mip-II (1-71) and the Antagonist N-Terminal Segment (1-10)
FEBS Lett., 489, 2001
5YAM
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BU of 5yam by Molmil
Solution structure of mice Met-CCL5/RANTES
Descriptor: C-C motif chemokine 5
Authors:Chen, Y.-C, Chen, S.-P, Lee, Y.-Z, Sue, S.-C.
Deposit date:2017-09-01
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
1VMP
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BU of 1vmp by Molmil
STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II
Descriptor: PROTEIN (ANTI-HIV CHEMOKINE MIP VII)
Authors:Liwang, A.C, Wang, Z.-X, Sun, Y, Peiper, S.C, Liwang, P.J.
Deposit date:1999-03-25
Release date:1999-11-24
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The solution structure of the anti-HIV chemokine vMIP-II.
Protein Sci., 8, 1999
1VMC
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BU of 1vmc by Molmil
STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA)
Descriptor: Stromal cell-derived factor 1
Authors:Gozansky, E.K, Clore, G.M.
Deposit date:2004-09-20
Release date:2005-03-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha.
J.Mol.Biol., 345, 2005
4OIJ
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BU of 4oij by Molmil
X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1
Descriptor: C-C motif chemokine 1, D-Ser-CCL1, SULFATE ION
Authors:Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H.
Deposit date:2014-01-19
Release date:2014-05-07
Last modified:2014-05-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4OIK
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BU of 4oik by Molmil
(Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ...
Authors:Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H.
Deposit date:2014-01-19
Release date:2014-05-07
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
6AEZ
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BU of 6aez by Molmil
Crystal structure of human CCL5 trimer
Descriptor: C-C motif chemokine 5, SULFATE ION
Authors:Chen, Y.C, Li, K.M, Chen, P.J, Zarivach, R, Sun, Y.J, Sue, S.C.
Deposit date:2018-08-07
Release date:2019-08-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
3N52
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BU of 3n52 by Molmil
crystal Structure analysis of MIP2
Descriptor: C-X-C motif chemokine 2
Authors:Rajasekaran, D.
Deposit date:2010-05-24
Release date:2011-06-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects.
Biochemistry, 51, 2012
6VGJ
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BU of 6vgj by Molmil
N-terminal variant of CXCL13
Descriptor: C-X-C motif chemokine 13
Authors:Rosenberg Jr, E.M, Lolis, E.J.
Deposit date:2020-01-08
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.
Acta Crystallogr D Struct Biol, 76, 2020
4LMQ
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BU of 4lmq by Molmil
Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Descriptor: Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain
Authors:Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N.
Deposit date:2013-07-10
Release date:2013-08-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.773 Å)
Cite:Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12.
Clin.Cancer Res., 19, 2013
4MHE
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BU of 4mhe by Molmil
Crystal structure of CC-chemokine 18
Descriptor: ACETATE ION, C-C motif chemokine 18
Authors:Liang, W.G, Tang, W.-J.
Deposit date:2013-08-29
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
1QE6
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BU of 1qe6 by Molmil
INTERLEUKIN-8 WITH AN ADDED DISULFIDE BETWEEN RESIDUES 5 AND 33 (L5C/H33C)
Descriptor: INTERLEUKIN-8 VARIANT, SULFATE ION
Authors:Gerber, N, Lowman, H, Artis, D.R, Eigenbrot, C.
Deposit date:1999-07-13
Release date:2000-03-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Receptor-binding conformation of the "ELR" motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 A resolution.
Proteins, 38, 2000
1QG7
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BU of 1qg7 by Molmil
STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA)
Descriptor: STROMAL CELL-DERIVED FACTOR 1 ALPHA, SULFATE ION
Authors:Senda, T, Nandhagopal, N, Sugimoto, K, Mitsui, Y.
Deposit date:1999-04-21
Release date:2001-02-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of recombinant native SDF-1alpha with additional mutagenesis studies: an attempt at a more comprehensive interpretation of accumulated structure-activity relationship data.
J.Interferon Cytokine Res., 20, 2000
1QNK
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BU of 1qnk by Molmil
TRUNCATED HUMAN GROB[5-73], NMR, 20 STRUCTURES
Descriptor: C-X-C motif chemokine 2
Authors:Qian, Y.Q, Johanson, K, McDevitt, P.
Deposit date:1999-10-18
Release date:2000-02-04
Last modified:2018-06-13
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8.
J. Mol. Biol., 294, 1999
6CWS
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BU of 6cws by Molmil
The NMR solution structure of CCL28
Descriptor: C-C motif chemokine 28
Authors:Thomas, M.A, Peterson, F.C, Volkman, B.F.
Deposit date:2018-03-30
Release date:2018-07-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Solution Structure of CCL28 Reveals Structural Lability that Does Not Constrain Antifungal Activity.
J. Mol. Biol., 430, 2018

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數據於2024-08-07公開中

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