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8G8R
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BU of 8g8r by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:monopartite p52 NLS in complex with Importin alpha 2
To Be Published
8G8S
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BU of 8g8s by Molmil
bipartite p52 NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:p52 bipartite NLS in complex with Importin alpha 2
To Be Published
6BWA
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BU of 6bwa by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
4BA3
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BU of 4ba3 by Molmil
mImp_alphadIBB_A89NLS
Descriptor: A89NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
Deposit date:2012-09-11
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
4B8J
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BU of 4b8j by Molmil
rImp_alpha1a
Descriptor: IMPORTIN SUBUNIT ALPHA-1A
Authors:Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
Deposit date:2012-08-28
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
6BVZ
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BU of 6bvz by Molmil
Importin alpha 3 in cargo free state
Descriptor: Importin subunit alpha-3
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
3ZIR
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BU of 3zir by Molmil
minor-site specific NLS (B141)
Descriptor: B141NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
6D7N
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BU of 6d7n by Molmil
Crystal structure of the W357R/W399R Importin alpha mutant
Descriptor: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1
Authors:Pedersen, L.C, London, R.E, Gabel, S.A.
Deposit date:2018-04-25
Release date:2019-03-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
1JPP
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BU of 1jpp by Molmil
The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin
Descriptor: ADENOMATOUS POLYPOSIS COLI PROTEIN, BETA-CATENIN, GLYCEROL
Authors:Spink, K.E, Fridman, S.G, Weis, W.I.
Deposit date:2001-08-02
Release date:2002-01-16
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex.
EMBO J., 20, 2001
6D7M
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BU of 6d7m by Molmil
Crystal structure of the W184R/W231R Importin alpha mutant
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ...
Authors:Pedersen, L.C, London, R.E, Gabel, S.A.
Deposit date:2018-04-25
Release date:2019-03-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
1LUJ
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BU of 1luj by Molmil
Crystal Structure of the Beta-catenin/ICAT Complex
Descriptor: Beta-catenin-interacting protein 1, Catenin beta-1
Authors:Graham, T.A, Clements, W.K, Kimelman, D, Xu, W.
Deposit date:2002-05-22
Release date:2002-10-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT.
Mol.Cell, 10, 2002
1M1E
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BU of 1m1e by Molmil
Beta-catenin armadillo repeat domain bound to ICAT
Descriptor: Beta-catenin, ICAT
Authors:Daniels, D.L, Weis, W.I.
Deposit date:2002-06-18
Release date:2002-10-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:ICAT inhibits Beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.
Mol.Cell, 10, 2002
8ECH
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BU of 8ech by Molmil
Tick-borne encephalitis virus capsid protein NLS bound to host importin alpha 2
Descriptor: Capsid protein C, Importin subunit alpha-1
Authors:Roby, J.A, Forwood, J.K.
Deposit date:2022-09-02
Release date:2022-09-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and biological functions of tick-borne encephalitis virus capsid protein
To Be Published
8F2Q
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BU of 8f2q by Molmil
Human Parvovirus B19 Nonstructural NS1 Protein NLS bound to Importin Alpha 2
Descriptor: Importin subunit alpha-1, Initiator protein NS1
Authors:Cross, E.M, Forwood, J.K.
Deposit date:2022-11-08
Release date:2023-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Importin alpha / beta-dependent nuclear transport of human parvovirus B19 nonstructural protein 1 is essential for viral replication.
Antiviral Res., 213, 2023
8EI9
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BU of 8ei9 by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H332, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H332, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EIC
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BU of 8eic by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H330, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H330, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EIB
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BU of 8eib by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H329, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H329, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.76 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8EIA
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BU of 8eia by Molmil
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H333, a Helicon Polypeptide
Descriptor: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H333, ...
Authors:Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H.
Deposit date:2022-09-14
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
8FUC
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BU of 8fuc by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2
Descriptor: Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein
Authors:Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
Deposit date:2023-01-17
Release date:2023-01-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FZM
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BU of 8fzm by Molmil
Human importin alpha 3 in complex with Bimax2 peptide
Descriptor: Bimax2, Importin subunit alpha-3
Authors:Donnelly, C.M, Forwood, J.K.
Deposit date:2023-01-29
Release date:2023-02-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human importin alpha 3 in complex with Bimax2 peptide
To Be Published
8FUA
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BU of 8fua by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1
Descriptor: Importin subunit alpha-1, Matrix protein
Authors:Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
Deposit date:2023-01-17
Release date:2023-02-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FZK
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BU of 8fzk by Molmil
Dimeric human importin alpha subunit
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION
Authors:Donnelly, C.M, Stewart, M, Forwood, J.K.
Deposit date:2023-01-29
Release date:2023-02-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dimeric human importin alpha subunit
To Be Published
8FK3
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BU of 8fk3 by Molmil
Adeno-Associated Virus Porcine Origin capsid protein basic regions in complex with Importin-alpha 2
Descriptor: Importin subunit alpha-1, VP1
Authors:Hoad, M, Forwood, J.K, Roby, J.A.
Deposit date:2022-12-20
Release date:2023-03-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Characterization of Porcine Adeno-Associated Virus Capsid Protein with Nuclear Trafficking Protein Importin Alpha Reveals a Bipartite Nuclear Localization Signal.
Viruses, 15, 2023
8FUB
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BU of 8fub by Molmil
Crystal structure of human Importin alpha 3 in complex with Hendra virus matrix protein NLS1
Descriptor: Importin subunit alpha-3, Matrix protein
Authors:Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
Deposit date:2023-01-17
Release date:2023-02-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
7RG1
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BU of 7rg1 by Molmil
Importin alpha2 in complex with MERS ORF4B H26A mutant
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Importin alpha2 in complex with MERS ORF4B NLS H26A mutant
To Be Published

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數據於2024-10-09公開中

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